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Fig. 3 | Breast Cancer Research

Fig. 3

From: Carbonic anhydrases reduce the acidity of the tumor microenvironment, promote immune infiltration, decelerate tumor growth, and improve survival in ErbB2/HER2-enriched breast cancer

Fig. 3

Extracellular and cytosolic carbonic anhydrases positively predict prognosis in HER2-enriched breast cancer, whereas extracellular carbonic anhydrases negatively predict prognosis in Basal-like breast cancer. A–L Survival curves for breast cancer patients (n = 860–2053) stratified for average mRNA expression of extracellular (A–D), cytosolic (E–H), and mitochondrial (I–L) carbonic anhydrases within each breast cancer molecular subtype. The ticks on the curves indicate censored subjects. Data were compared by log-rank test for trend. HR, hazard ratio

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Breast Cancer Research

ISSN: 1465-542X

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