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Table 2 Multivariate analysis of Dutch-cohort of TEAM for distant metastasis or death due to breast cancer (DM)

From: Ten-year distant-recurrence risk prediction in breast cancer by CanAssist Breast (CAB) in Dutch sub-cohort of the randomized TEAM trial

Variable

DM a,c,d (total cohort)

Hazard ratio (95% CI)

P value

Tumor stage

 T1

Reference

–

 T2-4

1.28 (0.85–1.93)

0.31

Lymph node status

 Negative

Reference

–

 Positive

1.19 (0.75–1.88)

0.54

Histological grade

 G1

Reference

 

 G2 + 3

2.07 (1.00–4.27)

0.10

CAB risk category

 Low-risk

Reference

–

 High-risk

2.54 (1.67–3.85)

< 0.001 b

  1. aModel undergone multivariate step-cox regression (both direction), adjusted for T stage (T2-4 vs T1), lymph nodal status (N+ vs N−), grade (G2 + 3 vs G1), and CAB risk score. Likelihood ratio was used to test whether the model was statistically significant. DM: distant metastasis or death due to breast cancer, CAB: CanAssist Breast. b P < 0.05. c Model likelihood ratio test = 24.59, P < 0.001. d There was only one patient who died due to breast cancer with only local recurrence, without distant metastasis