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Fig. 3 | Breast Cancer Research

Fig. 3

From: Molecular profiling of a real-world breast cancer cohort with genetically inferred ancestries reveals actionable tumor biology differences between European ancestry and African ancestry patient populations

Fig. 3

Differential Enrichment of Hallmark and Oncogenic Signature Gene Sets Between African and European Ancestry Patients (AA and EA, respectively). The volcano plots show all differentially expressed gene sets between AA and EA patients for A all breast cancer subtypes (n = 3433), B HR+/HER2- samples (n = 1502), and C triple-negative samples (n = 543). Gene sets were plotted by log fold-changes (logFC, x-axes) and limma P values (y-axes). Significance cutoffs were defined for each group, and gene sets with significantly different enrichment between ancestral groups were highlighted in green

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Breast Cancer Research

ISSN: 1465-542X

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