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Fig. 2 | Breast Cancer Research

Fig. 2

From: Molecular profiling of a real-world breast cancer cohort with genetically inferred ancestries reveals actionable tumor biology differences between European ancestry and African ancestry patient populations

Fig. 2

Differential Gene Expression Between Patients of African and European Ancestry (AA and EA, respectively). The volcano plots show all differentially expressed genes between AA and EA patients for A all breast cancer subtypes (n = 3433), B HR+/HER2- samples (n = 1502), and C triple-negative samples (n = 543). Gene sets were plotted by log fold-changes (logFC, x-axes) and meta P values (y-axes). Significance cutoffs were defined for each group, and gene sets with significantly different enrichment between ancestral groups were highlighted in green

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Breast Cancer Research

ISSN: 1465-542X

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