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Table 1 Main characteristics of the 5,262 FEDRA study women

From: Lifetime changes in body fatness and breast density in postmenopausal women: the FEDRA study

Characteristics

N (a)

Mean (SD) / %

Age at EPIC enrollment (years)

5262

49.03 (7.02)

Age at follow-up (years)

5262

58.93 (6.82)

Age at first digital mammographic examination (years)

5262

64.29 (6.41)

Volumetric percent density at first digital mammographic examination (%)

5262

7.84 (5.10)

Dense volume at first digital mammographic examination (cm3)

5262

47.71 (25.36)

Non-dense volume at first digital mammographic examination (cm3)

5262

701.05 (384.82)

Available digital mammographic examinations per woman (n)

5262

3.28 (1.63)

Women with four digital mammographic examination (n)

2316

44.0%

Age at menarche (years)

5249

12.38 (1.40)

Age at first birth (years)

4457

26.61 (4.34)

Parity (n)

 Nulliparous

224

4.8%

 One

1614

34.5%

 Two

2277

48.6%

 Three or more

566

12.1%

Breastfeeding (n) (among 4457 women with children)

3917

87.9%

Oral contraceptive (ever use) (n)

2791

53.2%

Postmenopause at EPIC enrollment (n)

2395

45.6%

Family history of breast cancer (n)

370

7.0%

Educational level at EPIC enrollment (n)

 None/elementary school

1192

22.8%

 Secondary/ professional school

1690

32.3%

 High school

1389

26.5%

 Degree

965

18.4%

Body height at EPIC enrollment (cm)

5203

160.3 (6.2)

Body weight (kg)

 At age 20 years

4379

54.3 (7.3)

 At age 40 years

4492

59.7 (8.6)

 At EPIC enrollment

5202

64.0 (10.6)

 At follow-up

5252

65.9 (11.4)

Body mass index (kg/m2)

 At age 20 years

4336

21.1 (2.5)

 At age 40 years

4443

23.2 (3.1)

 At EPIC enrollment

5201

24.9 (4.0)

 At follow-up

5193

25.7 (4.3)

Annual weight change (kg/years)

 From age 20 to 40

4036

0.3 (0.3)

 From age 40 to EPIC enrollmentb

3707

0.5 (1.3)

 From EPIC enrollment to follow-upc

5192

0.2 (0.6)

Weight change categories from age 20 to 40 (n)

 Weight gain > 10 kg

653

16.2%

 Weight gain > 5—≤ 10 kg

1054

26.1%

 Weight gain > 2—≤ 5 kg

1184

29.3%

 Stable weight (± 2 kg)

885

22.0%

 Weight loss > 2 kg

260

6.4%

Weight change categories from age 40 to EPIC enrollment (n)

 Weight gain > 10 kg

549

14.8%

 Weight gain > 5—≤ 10 kg

900

24.3%

 Weight gain > 2—≤ 5 kg

956

25.8%

 Stable weight (± 2 kg)

1055

28.4%

 Weight loss > 2 kg

247

6.7%

Weight change categories from EPIC enrollment to follow-up (n)

 Weight gain > 10 kg

296

5.7%

 Weight gain > 5—≤ 10 kg

844

16.3%

 Weight gain > 2—≤ 5 kg

1181

22.8%

 Stable weight (± 2 kg)

1931

37.1%

 Weight loss > 2 kg

940

18.1%

  1. a Because of some missing values not all reach the total number of participants
  2. b A total of 814 women enrolled before age 40 have been excluded. Mean 11.1 (SD 5.3) years between age 40 and EPIC enrollment
  3. c Mean 9.4 (SD 1.1) years between EPIC enrollment and follow-up