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Table 2 Socio-demographic, lifestyle, and clinical characteristics of women with breast cancer in the SABCHO cohort by the number of chronic conditions at breast cancer diagnosis

From: Multimorbidity and overall survival among women with breast cancer: results from the South African Breast Cancer and HIV Outcomes Study

 

Multimorbidity

 

No

Yes

Total

 

Number of chronic conditions

0–1

2

 ≥ 3

 

p value

Number of chronic conditions, N (row %)

N = 1796 (55.1)

N = 954 (29.2)

N = 511 (15.7)

N = 3261 (100.0)

 

Age in years

    

 < 0.001

 < 50

835 (46.5)

314 (32.9)

93 (18.2)

1,242 (38.1)

 

 ≥ 50

961 (53.5)

640 (67.1)

418 (81.8)

2,019 (61.9)

 

Ethnicity

    

 < 0.001

Asian

173 (9.6)

96 (10.1)

79 (15.5)

348 (10.7)

 

Black

1,414 (78.7)

770 (80.7)

385 (75.3)

2,569 (78.8)

 

Mixed

68 (3.8)

37 (3.9)

29 (5.7)

134 (4.1)

 

White

141 (7.9)

51 (5.3)

18 (3.5)

210 (6.4)

 

Marital status

    

 < 0.001

Not married

1,056 (58.8)

607 (63.6)

348 (68.1)

2,011 (61.7)

 

Married/Cohabiting

740 (41.2)

347 (36.4)

163 (31.9)

1,249 (38.3)

 

Highest level of education

    

 < 0.001

Primary education and below

464 (25.9)

307 (32.5)

206 (40.6)

977 (30.1)

 

Secondary education and above

1,327 (74.1)

639 (67.5)

302 (59.4)

2,268 (69.9)

 

Employment status

    

 < 0.001

Unemployed

1,249 (69.5)

709 (74.3)

413 (80.8)

2,371 (72.7)

 

Employed

547 (30.5)

245 (25.7)

98 (19.2)

890 (27.3)

 

Household socio-economic status (HSES)

    

0.299

0–5 (Low to medium)

1,380 (76.8)

739 (77.5)

378 (74.0)

2,497 (76.6)

 

6–7 (High)

416 (23.2)

215 (22.5)

133 (26.0)

764 (23.4)

 

aECOG

    

 < 0.001

0–1

1,656 (93.5)

873 (92.8)

444 (87.9)

2,973 (92.4)

 

2–4

115 (6.5)

68 (7.2)

61 (12.1)

244 (7.6)

 

bHospital

    

 < 0.001

CHBAH

709 (39.5)

358 (37.5)

162 (31.7)

1,229 (37.7)

 

CMJAH

482 (26.8)

218 (22.9)

85 (16.6)

785 (24.1)

 

Durban

269 (15.0)

181 (19.0)

130 (25.4)

580 (17.8)

 

Greys

299 (16.6)

172 (18.0)

123 (24.1)

594 (18.2)

 

Ngwelezana

37 (2.1)

25 (2.6)

11 (2.2)

73 (2.2)

 

Have you ever smoked?

    

0.187

No

1,565 (87.1)

850 (89.1)

440 (86.1)

2,855 (87.5)

 

Yes

231 (12.9)

104 (10.9)

71 (13.9)

406 (12.5)

 

Stage at diagnosis

    

0.044

Stages 1 and 2

728 (40.5)

388 (40.7)

237 (46.4)

1,353 (41.5)

 

Stage 3

736 (41.0)

415 (43.5)

188 (36.8)

1,339 (41.1)

 

Stage 4

332 (18.5)

151 (15.8)

86 (16.8)

569 (17.4)

 

cReceptor subtype

    

0.030

ER + /PR + HER2-

1,085 (60.4)

595 (62.7)

300 (58.8)

1,975 (60.8)

 

ER + /PR + HER2 + 

307 (17.2)

153 (16.1)

76 (14.9)

536 (16.5)

 

Er-&PR- HER2 + 

134 (7.5)

52 (5.5)

30 (5.9)

216 (6.7)

 

Er-&PR- HER2-

268 (15.0)

149 (15.7)

104 (20.4)

521 (16.0)

 

Surgery

    

0.463

No

613 (34.1)

307 (32.2)

163 (31.9)

1,083 (33.2)

 

Yes

1,183 (65.9)

647 (67.8)

348 (68.1)

2,178 (66.8)

 

Chemotherapy

    

0.001

No

419 (23.3)

213 (22.3)

155 (30.3)

787 (24.1)

 

Yes

1,377 (76.7)

741 (77.7)

356 (69.7)

2,474 (75.9)

 

Radiation therapy

    

0.143

No

920 (51.2)

515 (54.0)

284 (55.6)

1,719 (52.7)

 

Yes

876 (48.8)

439 (46.0)

227 (44.4)

1,542 (47.3)

 
  1. aECOG (Eastern Cooperative Oncology Group)
  2. bCHBAH (Chris Hani Baragwanath Academic Hospital), CMJAH (Charlotte Maxeke Johannesburg Academic Hospital)
  3. cER/PR (oestrogen receptor/progesterone receptor), HER2 (human epidermal growth factor receptor 2). Missing data: Highest level of education (n = 16), ECOG (n = 44), grade (n = 580), receptor subtype (n = 13)