Table 5 Analytical models used for breast cancer risk with breast texture features in addition to mammographic breast density for 5 studies using the contralateral breast (sorted by year)
References | Non-mammogram covariates included (e.g., age, parity, etc.) | Established confounders for density adjusted for | Prediction horizon (< 5 year/5 year/10 year) | AUC (baseline model) | Overall AUC (with texture features added) |
|---|---|---|---|---|---|
Ali et al. [26] | Age, BMI, density, HRT status, parity, age at first birth | Age, BMI, HRT use, and menopausal status | NR | 0.687 for apparent, 0.634 for honest | 0.703 for apparent, 0.643 for honest |
Wang et al. [45] | Adjusted for age, BMI | Age, BMI, HRT use, and menopausal status | NR | mC = 0.57 | mC = 0.58 |
Perez-Benito [39] | Percent density | Age | NR | 0.560 | 0.614 |
None and with age, percent density | Age | NR | Density only = 0.609 | 0.786 | |
Tan et al. [44] | None, with age only, and with age and BMI | Age and BMI | NR | Density = 0.52 | 0.68 |