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Fig. 4 | Breast Cancer Research

Fig. 4

From: METTL3 depletion contributes to tumour progression and drug resistance via N6 methyladenosine-dependent mechanism in HR+HER2—breast cancer

Fig. 4

Increasing of METTL3 inhibits BC cell growth in vivo. A Overexpression of METTL3 effectively inhibited HR+HER2− BC subcutaneous tumour growth and increased sensitivity to DOX in nude mice (n = 6). B The tumour weight was measured in the NC and METTL3 groups with or without DOX-treated. C and D Tumours were excised and processed for immunohistochemical staining and western blot for Ki-67, Vimentin and E-cadherin

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Breast Cancer Research

ISSN: 1465-542X

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