Fig. 2

a Illustration of the 3D data acquisition process. The linear array moves along the black dotted arrow to acquire 3D data at a step size of 0.5 mm. b Images acquired at each scanning step were processed and rendered to generate the 3D microvessel structure. c Quantitative parameters were extracted based on the 3D structure. Finally, the quantitative parameters could be input to the statistical model for lesion differentiation. HDMI = high-definition microvasculature imaging