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Table 2 GATA3, TRPS1, and MGP expression in metaplastic breast carcinomas

From: Matrix Gla protein (MGP), GATA3, and TRPS1: a novel diagnostic panel to determine breast origin

 

GATA3

MGP

TRPS1

Negative (n/%)

Positive (n/%)

Negative (n/%)

Positive (n/%)

Negative (n/%)

Positive (n/%)

Mild

Moderate

High

Mild

Moderate

High

Mild

Moderate

High

SqCC (n = 74)

28 (37.8)

16 (21.6)

16 (21.6)

14 (18.9)

10 (13.5)

18 (24.3)

22 (29.7)

24 (32.4)

1 (1.4)

4 (5.4)

10 (13.5)

59 (79.7)

SpCC (n = 18)

14 (77.8)

1 (5.6)

2 (11.1)

1 (5.6)

3 (16.7)

1 (5.6)

10 (55.6)

4 (22.2)

1 (5.6)

2 (11.1)

0 (0)

15 (83.3)

MBC-MD (n = 40)

27 (67.5)

10 (25.0)

3 (7.5)

0 (0)

3 (7.5)

4 (10.0)

13 (32.5)

20 (50.0)

0 (0)

1 (2.5)

4 (10.0)

35 (87.5)

FMC (n = 8)

5 (62.5)

3 (37.5)

0 (0)

0 (0)

0 (0)

2 (25.0)

4 (50.0)

2 (25.0)

1 (12.5)

1 (12.5)

3 (37.5)

3 (37.5)

  1. SqCC, squamous cell carcinoma; SpCC, spindle cell carcinoma; MBC-MD, metaplastic breast carcinoma with mesenchymal differentiation; FMC, fibromatosis-like metaplastic carcinoma