Fig. 2

SI-2 treatment inhibits the proliferation and activates apoptosis of E0771 breast tumor cells. A Expression levels of Ki67 in E0771 tumors from C57BL/6J mice treated with SI-2 (2.5 mg/kg) or vehicle were determined using IHC with an antibody against Ki67. The quantification of the percentage of labeled cells (PLC) positive for Ki67 in E0771 breast tumors is shown in the graph. B Expression levels of cleaved caspase 3 (CL CASP3) in E0771 tumors treated with SI-2 (2.5 mg/kg) or vehicle were determined using IHC with an antibody against cleaved caspase 3. The quantification of the PLC positive for CL CASP3 in E0771 tumors is shown in the graph