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Table 4 Relationship using dominant or recessive model between polymorphism and neuropathy

From: Tolerability of Eribulin and correlation between polymorphisms and neuropathy in an unselected population of female patients with metastatic breast cancer: results of the multicenter, single arm, phase IV PAINTER study

 

G0 N = 105

G1 N = 30

G2 N = 19

G3 N = 5

Fisher exact test (F) test for trend (T) P-value

rs2233335—NDRG1—model1—n (%)

G/G or G/T

79 (77.5)

12 (11.8)

7 (6.9)

4 (3.9)

F: < 0.001

T/T

26 (45.6)

18 (31.6)

12 (21.1)

1 (1.8)

T: < 0.001

rs2233335—NDRG1—model2—n (%)

G/G

25 (78.1)

2 (6.3)

3 (9.4)

2 (6.3)

F: 0.088

T/T or G/T

80 (63.0)

28 (22.0)

16 (12.6)

3 (2.4)

T: 0.210

rs7214723—CAMKK1—model1—n (%)

C/C or C/T

80 (70.8)

20 (17.7)

8 (7.1)

5 (4.4)

F: 0.008

T/T

23 (52.3)

10 (22.7)

11 (25.0)

0 (0.0)

T: 0.026

Missing

2

0

0

0

 

rs7214723—CAMKK1—model2—n (%)

C/C

32 (68.1)

8 (17.0)

5 (10.6)

2 (4.3)

F: 0.892

T/T or C/T

71 (64.5)

22 (20.0)

14 (12.7)

3 (2.7)

T: 0.729

Missing

2

0

0

0

 
  1. N: Number of subjects. G: Grade.