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Fig. 1 | Breast Cancer Research

Fig. 1

From: Deep whole genome sequencing identifies recurrent genomic alterations in commonly used breast cancer cell lines and patient-derived xenograft models

Fig. 1

Summary of single nucleotide variations (SNVs) in six breast cancer cell lines, including two replicates for MCF-7. A Classification of SNVs into different categories: overlap with 1000 genome project; overlap with dbSNP but not in 1000 genome project; cell-line specific events; B Distribution of the SNVs in MCF-7 in respect to location of protein coding genes. “RNA variant” are the variants that lie on one of the RNA transcripts C unsupervised hierarchical clustering of MCF7 in this study together with 27 MCF7 strains in Ben-David et al., based on their missense mutation obtained from supplementary information from (Ben-David et al.) D Percentage of overlapping missense mutations between our findings and those identified in multiple strains of MCF7s in Ben-David et al. E Venn diagram shows the overlap of missense mutations in Ben-David et al. and this study

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