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Fig. 1 | Breast Cancer Research

Fig. 1

From: Mammary collagen architecture and its association with mammographic density and lesion severity among women undergoing image-guided breast biopsy

Fig. 1

Collagen fibers were measured using second harmonic generation (SHG) microscopy in each of the selected regions of interest (ROIs) of H&E-stained WSI from diagnostic breast biopsy sections. Panel a illustrates ROI selection for a breast cancer case, with magnifications of the normal b and cancer d ROIs, and their corresponding SHG images of collagen fibers shown in Panels c and e. Panel f illustrates ROI selection for a benign breast disease control, with magnifications of the normal g and benign i ROIs, and their corresponding SHG images of collagen fibers shown in Panels h and j

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