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Table 3 Association between HIF-1α expression and breast cancer recurrence by ER/TAM group among 1682 subjects from the ProBe CaRe population-based case control study

From: Hypoxia-inducible factor-1α expression and breast cancer recurrence in a Danish population-based case control study

HIF-1α expression

ER+/TAM+ breast cancer patients

ER−/TAM− breast cancer patients

Recurrent cases/ controls

Adj. OR (95% CI)a

IPPW OR (95%CI)

Recurrent cases/

Adj. OR (95% CI)a

IPPW OR (95%CI)

Positive

106/93

1.21 (0.88, 1.67)

1.19 (0.87, 1.63)

122/122

0.97 (0.68, 1.39)

0.91 (0.60, 1.36)

Negative

352/371

Reference

Reference

136/132

Reference

Reference

  1. Adj., adjusted; CI, confidence interval; ER, estrogen receptor; HIF-1α, hypoxia-inducible factor 1; IPPW, inverse probability of participant weighting; OR, odds ratio; TAM, tamoxifen
  2. aAdjusted for matching factors (menopausal status, surgery date, county of residence, stage, age category) and chemotherapy, radiation therapy, and tamoxifen duration (ER+ stratum only)
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Breast Cancer Research

ISSN: 1465-542X

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