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Fig. 6 | Breast Cancer Research

Fig. 6

From: Quantitative single-cell analysis of immunofluorescence protein multiplex images illustrates biomarker spatial heterogeneity within breast cancer subtypes

Fig. 6

Spatial analysis of CD8 T-lymphocytes and CD20 B-lymphocytes. A Quantification of CD8 and CD20 lymphocytes presented as percentages of total cells in cancers categorized by IHC subtypes. Number of cores included in LumA (N = 24), LumB (N = 36), LumB, HER2+ (N = 6), HER2 (N = 13), TNBC (N = 22). B Quantitative evaluation of spatial arrangement. All cells in the core were classified as cancer, CD8 or CD20 lymphocytes. With neighborhood analysis, the percentages of neighboring cell types within 100 mm for each central CD8 or CD20 were quantified

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Breast Cancer Research

ISSN: 1465-542X

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