Fig. 5

Kaplan–Meier analyses generated using the GOBO online tool and centroid correlation clustering for the 64-gene matrisome signature (endpoint: distant metastasis free-survival (DMFS)) in (A) all breast cancers, (B) or the ER-positive (ER^pos) and (C) ER-negative (ER^neg) subgroup. (D–F) Multivariate analyses for the 64-gene signature (Day3 Preg) within same groups as above in the presence of other clinical parameters: size > 20 mm (Size), age > 50 years (Age), grade (G3), LN-status (LN^neg) and ER-status (ER^pos)