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Fig. 1 | Breast Cancer Research

Fig. 1

From: A matrisome RNA signature from early-pregnancy mouse mammary fibroblasts predicts distant metastasis-free breast cancer survival in humans

Fig. 1

(A) Hematoxylin/eosin staining of representative (n = 3 animals) 3-days pregnant mouse inguinal mammary glands (P3 A-C) show the histological changes compared to age-matched adult virgin glands (Ctrl A-C) of denser stromal adipose tissue () and wider ECM layer around epithelium (). Scale bars are 250 µm (B) Immunohistochemical analysis of 3-days pregnant mouse (n = 1 animal, 4th gland) mammary gland and age-matched adult virgin glands showing the changes of matrix- and basement membrane-associated proteins (COLI, COLVI, BMP1, FBLN2, FBLN5, and AGRN). Scale bars are 50 µm

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