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Fig. 6 | Breast Cancer Research

Fig. 6

From: Transcriptome analysis of heterogeneity in mouse model of metastatic breast cancer

Fig. 6

Single cell profiling revealed tissue-specific changes. A Dot plot analysis of cancer metabolic markers relevant to cancer progression for select clusters guided by the bulk RNA seq data. B Heat maps of differentially expressed genes relevant to cancer metabolism were identified across the pseudo-time using Monocle2. The color gradient indicates the average expression across the pseudo-time, trending from dark blue to red. Similar dot plot analyses and pseudo-time heat maps are shown for markers relevant to CD tumor microenvironment remodeling, EF stem cell signatures, and GH cell dormancy

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