Interaction Model | Hazard Ratio (95% CI) | P value |
---|---|---|
With BMI* | ||
PRS | 1.31 (1.18, 1.46) | 1.5 × 10–7 |
log(BMI) | 1.24 (1.12, 1.37) | 2.0 × 10–5 |
PRS*log(BMI) | 1.07 (0.97, 1.18) | 0.17 |
With smoking | ||
PRS | 1.24 (1.06, 1.44) | 4.0 × 10–3 |
Past smoker | 1.26 (1.00, 1.58) | 0.044 |
Current smoker | 1.72 (1.31, 2.27) | 9.1 × 10–5 |
PRS*past smoker | 1.23 (0.98, 1.53) | 0.069 |
PRS*current smoker | 1.03 (0.79, 1.34) | 0.82 |