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Table 5 Age- and residence-adjusted RR (95% CI) by quantiles of predicted risk in the test subcohort of China Kadoorie Biobank (CKB) and Shanghai Women’s Health Study (SWHS)

From: Development and external validation of a breast cancer absolute risk prediction model in Chinese population

  Overall Urban Rural Age < 50 years Age ≥ 50 years
Cases RR (95% CI) Cases RR (95% CI) Cases RR (95% CI) Cases RR (95% CI) Cases RR (95% CI)
Test subcohort of CKB (n = 100,274)
 1a 46 1.00 (reference) 16 1.00 (reference) 30 1.00 (reference) 18 1.00 (reference) 28 1.00 (reference)
 2 96 2.23 (1.53 to 3.24) 38 2.07 (1.15 to 3.76) 58 2.03 (1.21 to 3.39) 46 1.32 (0.76 to 2.32) 50 2.76 (1.64 to 4.64)
 3 105 2.60 (1.77 to 3.82) 52 2.44 (1.34 to 4.44) 53 2.11 (1.22 to 3.65) 52 1.30 (0.72 to 2.32) 53 3.38 (1.97 to 5.82)
 4 172 4.15 (2.84 to 6.08) 104 3.79 (2.11 to 6.83) 68 3.26 (1.87 to 5.71) 94 2.24 (1.25 to 4.01) 78 4.61 (2.67 to 7.95)
 5 277 6.74 (4.57 to 9.92) 237 5.72 (3.16 to 10.33) 40 5.21 (2.85 to 9.50) 121 2.87 (1.55 to 5.30) 156 8.30 (4.81 to 14.31)
SWHS (n = 73,203)
 1 185 1.00 (reference) -- -- -- -- 29 1.00 (reference) 156 1.00 (reference)
 2 237 1.36 (1.10 to 1.68) -- -- -- -- 145 1.00 (0.67 to 1.49) 92 1.38 (1.06 to 1.81)
 3 274 1.62 (1.31 to 2.02) -- -- -- -- 181 1.11 (0.75 to 1.65) 93 1.87 (1.42 to 2.46)
 4 308 1.89 (1.53 to 2.35) -- -- -- -- 182 1.32 (0.89 to 1.97) 126 2.07 (1.58 to 2.70)
 5 405 2.55 (2.06 to 3.16) -- -- -- -- 151 1.61 (1.06 to 2.43) 254 3.00 (2.34 to 3.84)
  1. Abbreviations: RR relative risk, CI confidence interval, -- not applicable
  2. Cox model was stratified by age in a 5-year interval in SWHS and additionally stratified by 10 study sites in CKB
  3. a1 refers to the lowest risk group, and 5 refers to the highest risk group