Table 5 Age- and residence-adjusted RR (95% CI) by quantiles of predicted risk in the test subcohort of China Kadoorie Biobank (CKB) and Shanghai Women’s Health Study (SWHS)
|  | Overall | Urban | Rural | Age < 50 years | Age ≥ 50 years | |||||
|---|---|---|---|---|---|---|---|---|---|---|
Cases | RR (95% CI) | Cases | RR (95% CI) | Cases | RR (95% CI) | Cases | RR (95% CI) | Cases | RR (95% CI) | |
Test subcohort of CKB (n = 100,274) | ||||||||||
 1a | 46 | 1.00 (reference) | 16 | 1.00 (reference) | 30 | 1.00 (reference) | 18 | 1.00 (reference) | 28 | 1.00 (reference) |
 2 | 96 | 2.23 (1.53 to 3.24) | 38 | 2.07 (1.15 to 3.76) | 58 | 2.03 (1.21 to 3.39) | 46 | 1.32 (0.76 to 2.32) | 50 | 2.76 (1.64 to 4.64) |
 3 | 105 | 2.60 (1.77 to 3.82) | 52 | 2.44 (1.34 to 4.44) | 53 | 2.11 (1.22 to 3.65) | 52 | 1.30 (0.72 to 2.32) | 53 | 3.38 (1.97 to 5.82) |
 4 | 172 | 4.15 (2.84 to 6.08) | 104 | 3.79 (2.11 to 6.83) | 68 | 3.26 (1.87 to 5.71) | 94 | 2.24 (1.25 to 4.01) | 78 | 4.61 (2.67 to 7.95) |
 5 | 277 | 6.74 (4.57 to 9.92) | 237 | 5.72 (3.16 to 10.33) | 40 | 5.21 (2.85 to 9.50) | 121 | 2.87 (1.55 to 5.30) | 156 | 8.30 (4.81 to 14.31) |
SWHS (n = 73,203) | ||||||||||
 1 | 185 | 1.00 (reference) | -- | -- | -- | -- | 29 | 1.00 (reference) | 156 | 1.00 (reference) |
 2 | 237 | 1.36 (1.10 to 1.68) | -- | -- | -- | -- | 145 | 1.00 (0.67 to 1.49) | 92 | 1.38 (1.06 to 1.81) |
 3 | 274 | 1.62 (1.31 to 2.02) | -- | -- | -- | -- | 181 | 1.11 (0.75 to 1.65) | 93 | 1.87 (1.42 to 2.46) |
 4 | 308 | 1.89 (1.53 to 2.35) | -- | -- | -- | -- | 182 | 1.32 (0.89 to 1.97) | 126 | 2.07 (1.58 to 2.70) |
 5 | 405 | 2.55 (2.06 to 3.16) | -- | -- | -- | -- | 151 | 1.61 (1.06 to 2.43) | 254 | 3.00 (2.34 to 3.84) |