| |
Test subcohort of CKB
|
SWHS
|
|---|
|
E
|
O
|
E/O (95% CI)
|
E
|
O
|
E/O (95% CI)
|
|---|
|
Overall
|
760
|
751
|
1.01 (0.94–1.09)
|
1320
|
1409
|
0.94 (0.89–0.99)
|
|
Age at enrollment, years
|
|
< 50
|
372
|
357
|
1.04 (0.94–1.16)
|
735
|
688
|
1.07 (0.99–1.15)
|
|
50–59
|
277
|
256
|
1.08 (0.96–1.23)
|
377
|
394
|
0.96 (0.87–1.06)
|
|
≥ 60
|
111
|
138
|
0.81 (0.68–0.96)
|
208
|
327
|
0.64 (0.57–0.71)
|
|
Residence
|
|
Rural
|
351
|
267
|
1.31 (1.17–1.49)
|
--
|
--
|
--
|
|
Urban
|
409
|
484
|
0.85 (0.77–0.93)
|
1320
|
1409
|
0.94 (0.89–0.99)
|
|
Highest education
|
|
Primary school or lower
|
333
|
299
|
1.11 (0.99–1.25)
|
143
|
195
|
0.73 (0.64–0.85)
|
|
Middle school
|
218
|
212
|
1.03 (0.90–1.18)
|
487
|
503
|
0.97 (0.89–1.06)
|
|
High school or higher
|
209
|
240
|
0.87 (0.77–0.99)
|
690
|
711
|
0.97 (0.90–1.05)
|
|
BMI, kg/m2
|
|
< 18.5
|
21
|
17
|
1.21 (0.76–2.08)
|
34
|
38
|
0.90 (0.66–1.27)
|
|
18.5–23.9
|
340
|
326
|
1.04 (0.94–1.17)
|
627
|
660
|
0.95 (0.88–1.03)
|
|
24.0–27.9
|
282
|
282
|
1.00 (0.89–1.13)
|
477
|
512
|
0.93 (0.85–1.02)
|
|
≥ 28
|
117
|
126
|
0.93 (0.78–1.12)
|
181
|
199
|
0.91 (0.79–1.05)
|
|
Height, cm
|
|
< 150.2
|
139
|
122
|
1.14 (0.96–1.38)
|
85
|
119
|
0.71 (0.59–0.86)
|
|
150.2–154.1
|
172
|
151
|
1.14 (0.97–1.35)
|
185
|
199
|
0.93 (0.81–1.07)
|
|
154.2–158.1
|
204
|
217
|
0.94 (0.82–1.08)
|
360
|
387
|
0.93 (0.84–1.03)
|
|
≥ 158.2
|
245
|
261
|
0.94 (0.83–1.06)
|
690
|
704
|
0.98 (0.91–1.06)
|
|
No. of first-degree relatives diagnosed with overall cancer
|
|
0
|
607
|
573
|
1.06 (0.98–1.15)
|
926
|
1023
|
0.91 (0.85–0.96)
|
|
1
|
126
|
144
|
0.87 (0.74–1.04)
|
316
|
329
|
0.96 (0.86–1.07)
|
|
≥ 2
|
27
|
34
|
0.80 (0.57–1.16)
|
77
|
57
|
1.35 (1.04–1.78)
|
|
No. of live birth
|
|
Nulliparous
|
14
|
12
|
1.17 (0.67–2.26)
|
52
|
58
|
0.89 (0.69–1.18)
|
|
1
|
340
|
353
|
0.96 (0.87–1.07)
|
852
|
822
|
1.04 (0.97–1.11)
|
|
≥2
|
406
|
386
|
1.05 (0.95–1.17)
|
416
|
529
|
0.79 (0.72–0.86)
|
|
Age at menarche, years
|
|
< 12
|
54
|
60
|
0.90 (0.70–1.19)
|
118
|
105
|
1.12 (0.93–1.37)
|
|
13–14
|
244
|
266
|
0.92 (0.81–1.04)
|
556
|
567
|
0.98 (0.90–1.07)
|
|
15–16
|
279
|
275
|
1.01 (0.90–1.15)
|
481
|
553
|
0.87 (0.80–0.95)
|
|
≥ 17
|
183
|
150
|
1.22 (1.04–1.45)
|
164
|
184
|
0.89 (0.77–1.04)
|
- Abbreviations: BMI body mass index, PY person-year, RR relative risk, CI confidence interval, E expected number of cases, O observed number of cases, -- not applicable
