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Table 1 Baseline characteristics of women by residence and dataset in China Kadoorie Biobank (CKB) and Shanghai Women’s Health Study (SWHS)

From: Development and external validation of a breast cancer absolute risk prediction model in Chinese population

 

CKB

SWHS

Rural

Urban

Urban

Derivation

Validation

Derivation

Validation

No. of participants, n

111,346

55,612

89,204

44,662

73,203

Cases, n

529

267

1007

484

1409

Age in years, mean (SD) and %

 Continuous, years

50.5 (10.2)

50.5 (10.2)

52.6 (10.7)

52.6 (10.7)

52.5 (9.1)

 30-

2.4

2.4

1.7

1.5

--

 35-

15.8

15.7

11.6

11.4

--

 40-

18.3

18.4

15.9

16.1

28.3

 45-

13.2

13.2

14.2

14.6

20.8

 50-

17.6

17.5

17.1

17.4

14.1

 55-

13.6

13.6

13.5

13.4

11.1

 60-

8.9

9.0

9.7

9.3

12.8

 65-

6.1

5.9

9.1

9.2

13.3

 70-

3.7

3.8

6.4

6.4

0.6

 75-

0.4

0.4

0.8

0.8

--

Highest education, %

 No formal school

31.9

31.5

17.3

17.1

10.6

 Primary school

40.3

40.5

20.4

20.0

10.8

 Middle school

21.6

21.6

29.9

30.4

37.2

 High school

5.6

5.8

23.2

23.3

28.0

 College/university

0.6

0.6

9.2

9.1

13.5

Ever smoker, %

5.6

5.5

4.4

4.6

2.8

Ever weekly drinker, %

3.2

3.2

2.6

2.6

2.3

BMI, mean (SD) and %

 Continuous, kg/m2

23.5 (3.4)

23.5 (3.4)

24.2 (3.5)

24.3 (3.5)

24.0 (3.4)

 < 18.5

5.2

5.1

3.2

3.0

3.4

 18.5–23.9

53.8

53.4

46.6

46.5

49.9

 24.0–27.9

31.2

31.6

36.1

36.3

34.6

 ≥ 28

9.9

9.9

14.0

14.2

12.2

Height, mean (SD) and %

 Continuous, cm

153.2 (5.9)

153.2 (5.9)

155.3 (5.9)

155.3 (5.9)

157.5 (5.5)

 < 150.2

29.4

29.4

19.3

19.1

10.3

 150.2–154.1

26.3

26.1

23.6

23.5

17.6

 154.2–158.1

24.1

24.3

26.1

26.1

27.9

 ≥ 158.2

20.2

20.1

31.0

31.3

44.2

No. of affected first-degree relatives, %

 0

85.2

85.5

80.6

80.4

74.7

 1

13.0

12.7

16.8

16.9

21.5

 ≥2

1.8

1.9

2.6

2.7

3.8

Postmenopausal, %

50.2

50.2

55.0

55.3

49.2

No. of live birth, mean (SD) and %

 Continuous

2.5 (1.4)

2.5 (1.4)

1.9 (1.2)

1.9 (1.2)

1.8 (1.2)

 Nulliparous

0.8

0.9

1.9

1.9

3.3

 1

21.1

21.3

50.8

51.2

54.9

 2

38.6

38.2

23.6

23.2

21.1

 ≥ 3

39.4

39.6

23.7

23.7

20.8

Age at menarche, mean (SD) and %

 Continuous, years

15.6 (1.9)

15.5 (1.9)

15.3 (2.0)

15.3 (2.0)

14.9 (1.7)

 < 12

4.7

4.7

6.4

6.4

6.3

 13–14

26.3

26.4

30.3

30.3

36.5

 15–16

38.3

38.4

36.1

36.1

39.5

 ≥ 17

30.6

30.5

27.2

27.3

17.8

Total months of breastfeeding, mean (SD) and %

 Continuous, months

42.4 (32.2)

42.5 (32.4)

24.0 (22.8)

23.9 (22.5)

15.5 (18.3)

 0

2.2

2.4

6.3

6.3

20.2

 1–23.9

36.5

36.5

64.1

64.1

56.6

 24–35.9

17.4

17.2

12.1

12.1

9.9

 36–47.9

14.2

14.0

7.0

7.1

5.9

 ≥ 48

29.6

29.9

10.4

10.3

7.4

Pill use, %

 Never

91.2

91.4

88.7

88.8

78.6

 Ever

8.8

8.6

11.3

11.2

20.4

  1. Abbreviations: SD standard deviation, MET metabolic equivalent of task, BMI body mass index