Sole adjuvant intraoperative breast radiotherapy in Taiwan: a single-center experience

Breast Cancer Research

Table 3 Univariate and multivariate analyses of risk factors for locoregional recurrence

	Crude HR (95% CI)	p value	Adjusted HR (95% CI)	p value
Radiotherapy type
EBRT	Reference		Reference
IORT	5.67 (1.29–24.93)	0.022	52.23 (3.37–809.99)	0.005
BMI
< 24	Reference		Reference
≥ 24	1.64 (0.39–6.85)	0.501	1.70 (0.28–10.20)	0.563
Age
< 50	Reference		Reference
50–59	0.48 (0.09–2.46)	0.375	0.13 (0.01–1.48)	0.101
≥ 60	0.38 (0.04–3.23)	0.374	0.15 (0.01–1.89)	0.142
Tumor size (mm)	1.00 (0.93–1.08)		1.01 (0.93–1.10)	0.810
Section margin
Negative	Reference		Reference
Positive	12.61 (2.44–65.08)	0.002	53.91 (3.02–962.98)	0.007
pN-stage
N0	Reference		Reference
N1 + 2	0.93 (0.11–7.71)	0.945	0.38 (0.05–2.73)	0.335
N3	11.32 (1.34–95.33)	0.026	0.28 (0.02–4.84)	0.382
ER/PR status
Negative	Reference		Reference
Positive	0.67 (0.14–3.34)	0.629	0.67 (0.08–5.50)	0.713
Her-2 status
Negative	reference		reference
Positive	2.96 (0.71–12.40)	0.137	6.06 (0.61–60.46)	0.125
Lymphovascular invasion
Negative	Reference		Reference
Positive	1.48 (0.33–6.60)	0.610	5.37 (0.88–32.87)	0.069

ISSN: 1465-542X