Table 1 Characteristics of female breast cancer patients in the discovery and validation sets
Baseline variable | Discovery set | Validation set | ||
|---|---|---|---|---|
Cases | Controls | Cases | Controls | |
(n = 20) | (n = 20) | (n = 19) | (n = 41) | |
Sex (Female) | 20 | 20 | 19 | 41 |
Mean age (years) | 59.2 ± 11.4 | 60.1 ± 7.3 | 60 ± 15.4 | 51 ± 6.3 |
Suspicious mammography with negative cytology | 4 | |||
Smoking status | ||||
Never | 12 | 19 | 19 | |
Former | 3 | 7 | ||
Current | 4 | 1 | 11 | |
NA | 1 | 4 | ||
Clinical stage | ||||
0 Tis N0 M0 | ||||
I T1 N0 M0 | 10 | 19 | ||
IIA T1 N1 M0 | 5 | |||
IIB T2 N1 M0 | 2 | |||
IIIA T0 N2 M0 | 3 | |||
ER | ||||
Positive/negative/NA | 9/−/11 | 10/4/5 | ||
PgR | ||||
Positive/negative/NA | 8/−/12 | 9/5/5 | ||
Her2 Neu | ||||
Positive/negative/NA | 10/7/3 | 10/4/5 | ||
Histologic grading | ||||
G1/G2/G3/NA | 0/8/5/7 | 2/12/5/0 | ||
Molecular subtype | ||||
Luminal/Her2-enriched/triple-negative/NA | 10/3/1/5 | |||
Comorbidities | ||||
None reported | 17 | 22 | ||
Diabetes (type I or type II) | 3 | |||
Allergy | 1 | |||
Thyroid nodules | 1 | |||
Hypothyroidism | 1 | 3 | ||
Chronic gastritis | 1 | |||
Depressive disorder | 2 | |||
Hypertension | 1 | 4 | ||
Hypotension | 1 | |||
Osteoporosis | 1 | |||
Hypocholesterolemia | 1 | |||
Epilepsy | 1 | |||
Arthrosis | 2 | |||
Asthma | 1 | |||