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Fig. 4 | Breast Cancer Research

Fig. 4

From: Local and distant tumor dormancy during early stage breast cancer are associated with the predominance of infiltrating T effector subsets

Fig. 4

Dormant tumor cells can be recovered from distant organs, ex vivo. Lungs that did not have any visible tumor were obtained from FVBN202 transgenic mice bearing primary tumor in the mammary region who received no treatment (Ctrl), FAC chemotherapy (FAC), or FAC chemotherapy followed by AIT and anti-PD-1 antibody therapy (FAC/AIT). MMC tumor cell line was used as positive control for the expression of neu. a Representative pictures of MMC and dormant tumor cells recovered from the lungs. b Gated FVS− viable cells were analyzed for the detection of neu+ cells. c Gated FVS− neu+ viable cells were analyzed for the expression of EpCAM. d Gated FVS− viable cells were analyzed for the expression of CD44 and CD24. Data represents triplicates

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Breast Cancer Research

ISSN: 1465-542X

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