Table 4 Subgroup analysis according to PET timing and parameters
Outcomes | PET timing | PET parameter | Studies (n) | Pooled hazard ratios | 95% confidence interval | I2 (%) | P for subgroup difference |
|---|---|---|---|---|---|---|---|
Disease-free survival | Interim | %ΔSUVmax | 9 | 0.20 | 0.13–0.31 | 0 | 0.8539 |
|  |  | SUVmax | 1 | 0.24 | 0.07–0.82 | NA |  |
|  |  | CMR | 2 | 0.31 | 0.07–1.37 | 32 |  |
|  | Post-treatment | %ΔSUVmax | 2 | 0.16 | 0.05–0.48 | 0 | 0.5821 |
|  |  | %ΔSUVpeak | 1 | 0.16 | 0.02–1.28 | NA |  |
|  |  | %ΔMTV | 1 | 0.39 | 0.19–0.79 | NA |  |
|  |  | ΔSUVmax | 2 | 0.38 | 0.19–0.78 | 0 |  |
|  |  | CMR | 3 | 0.25 | 0.12–0.50 | 0 |  |
Overall survival | Interim | %ΔSUVmax | 3 | 0.20 | 0.09–0.44 | 0 | 0.7303 |
|  |  | CMR | 1 | 0.34 | 0.02–6.64 | NA |  |
|  | Post-treatment | SUVmax | 1 | 0.30 | 0.11–0.81 | NA | 0.7373 |
|  |  | CMR | 2 | 0.24 | 0.10–0.59 | 0 |  |