Fig. 1

Multivariable associations of statin and metformin use and mammographic breast density. Parameter estimates and 95% confidence intervals for percent density (a), centimeter square dense area (b), centimeter square non-dense area (c), and high density BI-RADS (d) with statin and metformin use in separate fully adjusted models (left panel) as well as fully adjusted co-medication category models (right panel, reference group used neither metformin nor statin). All models adjust for age, BMI, education, race, menopausal status, age at first live birth, and insulin use