|
Fractionation
|
Hypofractionation
|
Normofractionation
|
|---|
|
Group
|
KD (N = 6)
|
SD (N = 6)
|
p value
|
KD (N = 23)
|
SD (N = 24*)
|
p value
|
|---|
|
Δ Body weight [kg]
|
− 2.7 ± 1.2
|
0.7 ± 1.2
|
0.0043
|
− 2.9 ± 2.2
|
0.4 ± 1.3
|
7.9 × 10−7
|
|
Δ Fat mass [kg]
|
− 1.2 ± 0.5
|
0.1 ± 0.6
|
0.0087
|
− 2.3 ± 1.7
|
0.1 ± 1.3
|
9.1 × 10−6
|
|
Δ Fat free mass [kg]
|
− 1.5 ± 2.4
|
0.6 ± 1.1
|
0.065
|
− 0.6 ± 1.3
|
0.3 ± 1.2
|
0.030
|
|
Δ Skeletal muscle mass [kg]
|
− 1.1 ± 1.7
|
0.5 ± 0.7
|
0.015
|
− 0.6 ± 0.8
|
0.1 ± 0.5
|
0.0012
|
|
Δ Phase angle [°]
|
− 0.25 ± 0.82
|
0.06 ± 0.18
|
0.75
|
0.06 ± 0.29
|
0.05 ± 0.24
|
1
|
|
Δ Extracellular water [l]
|
− 0.2 ± 0.7
|
0.2 ± 0.3
|
0.52
|
− 0.3 ± 0.6
|
0.1 ± 0.7
|
0.033
|
|
Δ Intracellular water [l]
|
− 0.9 ± 1.6
|
0.4 ± 0.6
|
0.025
|
− 0.5 ± 0.9
|
0.1 ± 0.4
|
0.0040
|
|
Δ Total body water [l]
|
− 1.1 ± 1.4
|
0.6 ± 0.9
|
0.065
|
− 0.7 ± 1.1
|
0.2 ± 0.9
|
0.010
|
|
Δ β-hydroxybutyrate [mmol/l]
|
0.2 ± 0.2
|
− 0.03 ± 0.04
|
0.044
|
0.6 ± 0.7
|
0.1 ± 0.5
|
8.2 × 10−7
|
|
Δ Insulin
|
2.3 ± 7.5
|
− 1.9 ± 1.7
|
0.297
|
− 2.1 ± 5.9
|
− 0.5 ± 3.3
|
0.412
|
|
Δ IGF-1
|
− 23.2 ± 45.8
|
− 28.2 ± 30.9
|
0.294
|
− 22.9 ± 61.5
|
− 9.8 ± 40.9
|
0.116
|
|
Δ T3
|
− 0.25 ± 0.25
|
− 0.07 ± 0.05
|
0.310
|
− 0.48 ± 0.29
|
− 0.09 ± 0.38
|
0.0012
|
- Body composition changes (Δ) from baseline to final measurement according to fractionation schedule which determined the study length. Significant differences between the KD and SD groups are highlighted in bold
- *In the SD group, there was one patient with missing estimates at the final measurement except for body weight and phase angle because a wrong height had been inserted into the BIA device. This patient is only used for the calculations of body weight and phase angle changes
