|
Covariate
|
Extracellular water
|
Intracellular water
|
Total body water
|
|---|
|
Coefficient
|
p value
|
Coefficient
|
p value
|
Coefficient
|
p value
|
|---|
|
Time
|
− 0.05 ± 0.02 l/week
|
0.024
|
− 0.01 ± 0.02 l/week
|
0.76
|
− 0.05 ± 0.03 l/week
|
0.13
|
|
KD: yes
|
− 0.6 ± 0.2 l
|
3.2 × 10−5
|
− 0.5 ± 0.2 l
|
0.0014
|
− 1.2 ± 0.2 l
|
1.2 × 10−7
|
|
Time × KD
|
0.09 ± 0.03 l/week
|
0.011
|
− 0.001 ± 0.03 l/week
|
0.97
|
0.08 ± 0.06 l/week
|
0.16
|
|
Baseline BMI
|
− 0.1 ± 0.2 l/10 kg/m2
|
0.57
|
0.4 ± 0.2 l/10 kg/m2
|
0.045
|
0.2 ± 0.3 l/10 kg/m2
|
0.49
|
|
Time × MAP
|
− 0.004 ± 0.03 l
|
0.91
|
− 0.03 ± 0.04 l
|
0.47
|
− 0.02 ± 0.06 l
|
0.69
|
|
Age
|
0.05 ± 0.06 l/10 years
|
0.38
|
− 0.2 ± 0.1 l/10 years
|
0.0017
|
− 0.14 ± 0.09 l/10 years
|
0.099
|
|
PTV
|
0.2 ± 0.1 l/500 ccm
|
0.15
|
0.01 ± 0.13 l/500 ccm
|
0.96
|
0.1 ± 0.2 l/500 ccm
|
0.48
|
|
Conditional R2
|
0.982
|
0.981
|
0.988
|
|
Marginal R2
|
0.927
|
0.922
|
0.953
|
- Regression coefficient estimates are given with their standard error and associated p value. Note that the average time trends for the SD and KD groups are given by the regression coefficients corresponding to “Time” and “Time” + “Time × KD,” respectively. BMI body mass index, KD ketogenic diet, MAP Master Amino Acid Pattern supplement, PTV planning target volume
