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Table 3 Regression coefficients and R2 values of the full models fitted to the water composition changes

From: Impact of a ketogenic diet intervention during radiotherapy on body composition: III—final results of the KETOCOMP study for breast cancer patients

Covariate Extracellular water Intracellular water Total body water
Coefficient p value Coefficient p value Coefficient p value
Time − 0.05 ± 0.02 l/week 0.024 − 0.01 ± 0.02 l/week 0.76 − 0.05 ± 0.03 l/week 0.13
KD: yes − 0.6 ± 0.2 l 3.2 × 10−5 − 0.5 ± 0.2 l 0.0014 − 1.2 ± 0.2 l 1.2 × 10−7
Time × KD 0.09 ± 0.03 l/week 0.011 − 0.001 ± 0.03 l/week 0.97 0.08 ± 0.06 l/week 0.16
Baseline BMI − 0.1 ± 0.2 l/10 kg/m2 0.57 0.4 ± 0.2 l/10 kg/m2 0.045 0.2 ± 0.3 l/10 kg/m2 0.49
Time × MAP − 0.004 ± 0.03 l 0.91 − 0.03 ± 0.04 l 0.47 − 0.02 ± 0.06 l 0.69
Age 0.05 ± 0.06 l/10 years 0.38 − 0.2 ± 0.1 l/10 years 0.0017 − 0.14 ± 0.09 l/10 years 0.099
PTV 0.2 ± 0.1 l/500 ccm 0.15 0.01 ± 0.13 l/500 ccm 0.96 0.1 ± 0.2 l/500 ccm 0.48
Conditional R2 0.982 0.981 0.988
Marginal R2 0.927 0.922 0.953
  1. Regression coefficient estimates are given with their standard error and associated p value. Note that the average time trends for the SD and KD groups are given by the regression coefficients corresponding to “Time” and “Time” + “Time × KD,” respectively. BMI body mass index, KD ketogenic diet, MAP Master Amino Acid Pattern supplement, PTV planning target volume