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Table 5 Summary of multivariate analysis in all patients without neoadjuvant chemotherapy showing the odds ratio (95% confidence interval) of variables significantly associated with PD-L1 scoring methods and sTIL level

From: Comparison of three scoring methods using the FDA-approved 22C3 immunohistochemistry assay to evaluate PD-L1 expression in breast cancer and their association with clinicopathologic factors

Factor

TC

TCIC

IC

sTIL level

Age

 ≥ 50 vs. < 50 years

   

0.50 (0.27, 0.92)a

Race/ethnicity

 White+Latino vs. Black

 

0.32 (0.14, 0.74)b

0.21 (0.09, 0.53)c

 

 Others vs. Black

 

NS

NS

 

Histologic grade

 3 vs. 1 + 2

3.31 (1.38,7.93)b

  

4.69 (2.57, 8.57)c

sTIL level

 ≥ 10% vs. < 10%

3.48 (1.50, 8.11)b

12.44 (6.59, 23.49)c

23.12 (10.60, 50.42)c

 

Receptor group

 ER/PR pos vs. TNBC

   

0.20 (0.10, 0.43)c

 HER2 vs. TNBC

   

NS

  1. NS not significant
  2. aP value < 0.05–0.01
  3. bP value < 0.01–0.001
  4. cP value < 0.001