Table 2 Univariate Cox proportional regression analysis on 5-year overall and disease-free survival of 103 LABC patients
From: Clinical and functional significance of tumor/stromal ATR expression in breast cancer patients
Parameter | Overall survival | Disease-free survival | ||||
|---|---|---|---|---|---|---|
Hazard ratio | 95% Cl† | P* | Hazard ratio | 95% Cl† | P* | |
ATR (fibroblasts) | ||||||
High | 1.000 | 1.000 | ||||
Low | 7.934 | 2.950–21.340 | 0.0001 | 0.406 | 0.198–0.833 | 0.0140 |
ATR (epithelial cells) | ||||||
High | 1.000 | 1.000 | ||||
Low | 7.711 | 2.244–26.498 | 0.0012 | 0.732 | 0.422–1.270 | 0.2670 |
Tumor size | ||||||
≤ 5 cm | 1.000 | 1.000 | ||||
> 5 cm | 1.239 | 0.439–3.500 | 0.6852 | 0.796 | 0.452–1.404 | 0.4311 |
Age | ||||||
≤ 52 years | 1.000 | 1.000 | ||||
> 52 years | 0.984 | 0.940–1.030 | 0.4826 | 1.012 | 0.985–1.039 | 0.3854 |
Stage | ||||||
T2 | 1.000 | 1.000 | ||||
T3, T4, Tx | 1.941 | 0.642–5.866 | 0.2401 | 0.508 | 0.292–0.883 | 0.0163 |
Grade | ||||||
I/II | 1.000 | 1.000 | ||||
Ш/poorly differentiated | 1.949 | 0.758–5.012 | 0.1660 | 1.241 | 0.723–2.130 | 0.4328 |