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Table 2 Summary of clinical response from baseline to week 24

From: Efficacy of neoadjuvant endocrine therapy compared with neoadjuvant chemotherapy in pre-menopausal patients with oestrogen receptor-positive and HER2-negative, lymph node-positive breast cancer

Clinical response

Intention to treat population

Chemotherapy group (n = 87)

Endocrine therapy group (n = 87)

MRI+

  CR

14 (16.3%)

2 (2.3%)

  PR

58 (67.4%)

43 (50.6%)

  CR + PR

72 (83.7)

45 (52.9%)

Calliper*

  CR

27 (31%)

17 (19.5%)

  PR

46 (52.9%)

45 (51.5%)

  CR + PR

73 (83.9%)

62 (71.3%)

Pathologic response

Chemotherapy group (n = 87)

Endocrine therapy group (n = 83)

 pCR

3 (3.4%)

1 (1.2%)

 pCR (breast)

5 (5.7%)

1 (1.2%)

 pCR (axillary lymph node)

12 (13.8%)

4 (4.9%)

  1. Data are n (%). CR complete response, PR partial response
  2. +Estimated difference 30.8%, 95% CI 17.6–44.0, p < 0.001
  3. *Estimated difference 12.6%, 95% CI 0.4–24.9, p = 0.046