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Fig. 2 | Breast Cancer Research

Fig. 2

From: In utero estrogenic endocrine disruption alters the stroma to increase extracellular matrix density and mammary gland stiffness

Fig. 2

Collagen genes are more highly expressed in BPA-exposed mammary glands. a A heatmap showing the RNA expression of the most abundantly expressed collagen genes is depicted. Collagen genes are ordered from top to bottom based upon the average normalized read counts in the control samples. **padj < 0.05; *p < 0.05 b Collagen genes that had increased expression in our RNA-seq dataset were validated on an additional 3 cohorts of mice using qPCR. Average normalized mean expression ± SD is graphed. *p < 0.05

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Breast Cancer Research

ISSN: 1465-542X

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