Table 2 Classification results (F1-scores) for testing ST-TC signatures with MC-SVM. The column “Dataset” indicates the sample on which the model was tested while the three remaining datasets were used for model training
From: Identification and transfer of spatial transcriptomics signatures for cancer diagnosis
(A) Manually selected ST spots with DE ST-TCs | (B) Manually selected ST spots with all ST-TCs | (C) ST spots from unsupervised clustering with all ST-TCs | |||||||
|---|---|---|---|---|---|---|---|---|---|
Dataset | Non-mal. | DCIS | IDC | Non-mal. | DCIS | IDC | Non-mal. | DCIS | IDC |
1 | 0.93 | 1.00 | 0.92 | 0.95 | 0.98 | 0.97 | 0.96 | 0.97 | 0.93 |
2 | 1.00 | 1.00 | 1.00 | 0.98 | 1.00 | 0.97 | 0.96 | 0.91 | 0.92 |
3 | 0.97 | 1.00 | 0.95 | 1.00 | 1.00 | 1.00 | 0.95 | 0.96 | 0.86 |
4 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 0.96 | 0.97 | 0.93 |
Avg | 0.97 | 1.00 | 0.96 | 0.98 | 0.99 | 0.98 | 0.95 | 0.95 | 0.91 |