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Table 2 Incidence rates (IRs, per 1000 person-months) and incidence rate ratios (IRRs) of psychiatric disorders and cardiovascular diseases during the 6 weeks before diagnosis of women that underwent a breast diagnostic workup, a population-based cohort study during 2005–2014 in Skåne, Sweden

From: Psychiatric disorders and cardiovascular diseases during the diagnostic workup of potential breast cancer: a population-based cohort study in Skåne, Sweden

 

No. of events

Crude IR

IRR (95% CI)

Psychiatric disorder

 Reference group*

954,351

17.6

1.0

 Unspecified lump in breast

578

26.4

1.1 (1.0–1.2)

 Benign tumor

155

25.2

1.3 (1.1–1.5)

 Breast cancer

278

24.0

1.4 (1.2–1.6)

  T0N0M0/stage 0/stage I

149

24.5

1.4 (1.1–1.6)

  Stage II

95

22.5

1.4 (1.1–1.7)

  Stages III and IV

29

31.8

1.8 (1.2–2.6)

  Missing stage

5

13.3

1.0 (0.4–2.5)

Cardiovascular disease

 Reference group*

1,094,327

20.1

1.0

 Unspecified lump in breast

297

13.6

1.1 (1.0–1.2)

 Benign tumor

116

18.9

1.3 (1.1–1.6)

 Breast cancer

777

67.2

1.9 (1.8–2.0)

  T0N0M0/stage 0/stage I

334

55.0

1.7 (1.5–1.9)

  Stage II

284

67.4

1.8 (1.6–2.1)

  Stages III and IV

115

126.5

2.8 (2.4–3.3)

  Missing stage

44

118.0

2.9 (2.1–3.9)

  1. IR incidence rate, IRR incidence rate ratio
  2. *Reference group included person-time accumulated from women who did not have any breast diagnostic workup during the follow-up and the person-time accumulated before the start of workup from women with a breast diagnostic workup during the follow-up
  3. CI confidence interval. IRRs were estimated using Poisson regression, by using attained age as the underlying timescale and adjusting for cohabitation status, registered parish as a proxy for socioeconomic status, and preexisting psychiatric disorders (for outcome of psychiatric disorders) or preexisting cardiovascular diseases (for outcome of cardiovascular diseases)