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Table 1 The distribution of rs12628403 genotype by tumor subtypes in the Hong Kong breast cancer study (HKBC) and TCGA white population

From: Immune gene expression profiling reveals heterogeneity in luminal breast tumors

 

Low-TIL, N (%)

High-ISG, N (%)

High-TIL, N (%)

HER2+basal, N (%)

HKBC

A/A

10 (29.4%)

9 (32.2%)

3 (21.4%)

15 (46.9%)

A/C

17 (50.0%)

15 (53.5%)

8 (57.2%)

13 (40.6%)

C/C

7 (20.6%)

4 (14.3%)

3 (21.4%)

4 (12.5%)

P value*

Ref

0.89

0.92

0.35

TCGA White

A/A

111 (90.3%)

117 (86.0%)

60 (85.7%)

158 (92.9%)

A/C

11 (8.9%)

18 (13.3%)

10 (14.3%)

10 (5.9%)

C/C

1 (0.8%)

1 (0.7%)

0 (0%)

2 (1.2%)

P value*

Ref

0.66

0.44

0.62

  1. *P values were obtained from Fisher’s exact test by comparing each immune subtype with low-TIL