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Table 1 Risk factors and clinical characteristics of cases and controls. Cases are also shown stratified by tumor size

From: Automated volumetric breast density measures: differential change between breasts in women with and without breast cancer

 

Overall cases (N = 1160)

Tumor size

 

≤ 2 cm (N = 860)

2.1–5 cm (N = 243)

> 5 cm (N = 36)

Controls (N = 2360)

Age, median (Q1, Q3)*

61.0 (53, 70)

61.1 (53, 71)

60.0 (52, 69)

57.7 (50, 67)

61.4 (54, 70)

Body mass index, median (Q1, Q3)*

25.8 (22.7, 30.5)

25.8 (22.8, 30.3)

26.4 (22.5, 30.8)

28.6 (24.4, 32.9)

25.8 (22.9, 30.2)

Race

 White

943 (81.3%)

706 (82.1%)

193 (79.4%)

32 (88.9%)

2028 (85.9%)

 Asian

139 (12.0%)

95 (11.0%)

37 (15.2%)

2 (5.6%)

203 (8.6%)

 African-American

26 (2.2%)

18 (2.1%)

6 (2.5%)

0 (0.0%)

39 (1.7%)

 Hispanic

21 (1.8%)

17 (2.0%)

3 (1.2%)

0 (0.0%)

43 (1.8%)

 Others/mixed

31 (2.7%)

24 (2.8%)

4 (1.6%)

2 (5.6%)

47 (2.0%)

Interval between mammograms, median (Q1, Q3)

3.0 (1.9, 3.9)

3.0 (1.9, 4.0)

3.0 (1.9, 3.9)

2.9 (1.6, 3.9)

3.1 (2.0, 4.1)

First degree family Hx B.C.*

317 (27.6%)

247 (29.1%)

59 (24.5%)

6 (16.7%)

479 (20.4%)

Post-menopausal* (age 55+)

805 (69.4%)

605 (70.3%)

161 (66.3%)

21 (58.3%)

1675 (71.0%)

Screening mammogram within 2 months of diagnosis

1043 (90%)

784 (91%)

212 (87%)

27 (75%)

–

BI-RADS density*

 a

132 (12.9%)

107 (14.1%)

20 (9.5%)

3 (10.0%)

463 (20.5%)

 b

408 (40.0%)

309 (40.6%)

81 (38.6%)

9 (30.0%)

973 (43.1%)

 c

391 (38.3%)

275 (36.1%)

94 (44.8%)

17 (56.7%)

684 (30.3%)

 d

89 (8.7%)

70 (9.2%)

15 (7.1%)

1 (3.3%)

138 (6.1%)

VPD (%)*

 Median

6.9

6.6

8.1

9.0

5.9

 Q1, Q3

4.8, 11.3

4.6, 10.8

5.2, 12.9

5.7, 12.8

4.3, 9.7

 Range

(2.3–36.0)

(2.3–36.0)

(2.4–29.7)

(3.3–24.8)

(2.0–36.3)

DV (cm3)*

 Median

56.0

53.5

62.6

81.6

47.7

 Q1, Q3

41.5, 79.4

40.0, 73.5

45.1, 90.4

62.2, 110.7

35.9, 64.8

 Range

(12.4–281.1)

(12.4–265.4)

(17.7–212.6)

(22.2–199.2)

(10.8–314.8)

  1. Twenty-one case subjects with unknown tumor size, 50 case subjects with unknown BMI, 13 case subjects with unknown family history, 140 subjects with unknown BI-RADS density
  2. BI-RADS Breast Imaging Reporting and Data System 4th edition, VPD volumetric percent density, DV dense volume
  3. *Determined at the time of the earliest mammogram