Fig. 5

CRYβB2 alters breast cancer cell growth behaviors in 3D cell culture. a Cells were grown in Matrigel and live cell growth imaged over time. Representative images were taken at day 10 of growth. Data is one representative assay of a minimum of four independent experiments from both SUM159 and Hs578t models. b Data are mean sphere area of the representative 159 models ± SEM. *p < 0.008, one-way ANOVA with Bonferroni test. +C, CRYβB2 overexpression; +P1, CRYβB2P1 overexpression; P-/-, CRYβB2P1 knockout C-/-, CRYβB2 knockout; +C+P1, CRYβB2 and CRYβB2P1 dual overexpression