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Fig. 3 | Breast Cancer Research

Fig. 3

From: Profiling molecular regulators of recurrence in chemorefractory triple-negative breast cancers

Fig. 3

Immune depletion analysis. a Immune upstream regulator analysis. Differential in silico regulator activity as called by Ingenuity Pathway Analysis. Regulator confidence (p-values) are relayed in gray with accompanying Z-scores relayed in orange (upregulated) or blue (downregulated) (n = 24 pairs). b, c Hematoxylin and eosin-stained tissues from before (b) and after (c) chemotherapy demonstrating a decrease in total lymphocytes. d Unpaired (left) and paired (right) total lymphocyte% as called before and after surgery (unpaired: n = 67,83, p = 0.04; paired: n = 49, p = 0.04). e Paired total lymphocyte% in non-relapsers (left) and relapsers (right) (non-relapse: n = 20, p = 0.01; relapse: n = 28, p = 0.10). d and e were performed with Student’s t test

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