Association between C-reactive protein and radiotherapy-related pain in a tri-racial/ethnic population of breast cancer patients: a prospective cohort study

Table 4 CRP levels by pre- and post-RT pain stratified by obesity

BMI	Pre-RT pain	Post RT pain	N	Pre-RT CRP				Post-RT CRP
BMI	Pre-RT pain	Post RT pain	N	Mean	SD	Median	P ¹	Mean	SD	Median	P ¹	P ²
NA	No	No	194	5.5	8.4	3.3	0.278	5.2	7.9	3.2	0.034	0.675
NA	No	Yes	57	7.1	8.8	3.4		7.2	10.8	4.8		0.936
NA	Yes	No	20	5.4	9.2	2.2	0.010	5.6	9.5	3.3	0.075	0.807
NA	Yes	Yes	34	10.8	12.1	6.0		8.8	10.2	5.6		0.278
< 30	No	No	130	5.1	9.2	2.6	0.786	4.4	8.1	2.0	0.169	0.423
< 30	No	Yes	31	5.4	8.1	2.7		7.4	14.1	3.2		0.366
< 30	Yes	No	10	4.4	7.0	2.2	0.393	3.6	2.4	3.1	0.647	0.676
< 30	Yes	Yes	11	12.1	16.8	3.6		7.5	11.5	4.2		0.304
≥ 30	No	No	64	6.3	6.3	4.6	0.480	6.9	7.1	4.8	0.368	0.497
≥ 30	No	Yes	26	9.0	9.5	5.9		6.9	4.8	5.9		0.259
≥ 30	Yes	No	10	6.4	11.3	2.7	0.022	7.7	13.3	3.5	0.142	0.114
≥ 30	Yes	Yes	23	10.1	9.4	6.4		9.4	9.7	6.9		0.677

¹Unadjusted P value from the Wilcoxon two-sample test (comparing 2 groups by pain status)
²P value from the paired t test within each group (comparing pre-RT and post-RT CRP). Significant findings are in italics

ISSN: 1465-542X