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Table 2 CRP levels by patient, treatment characteristics, and pain status

From: Association between C-reactive protein and radiotherapy-related pain in a tri-racial/ethnic population of breast cancer patients: a prospective cohort study

Variable Pre-RT CRP (mg/L) Post-RT CRP (mg/L)
N Mean SD MD P 1 N Mean SD MD P 1
Study population 362 6.5 9.3 3.5   338 6.1 8.9 3.5 0.6462
Race/ethnicity
 NHW 58 6.1 12.4 2.8 0.879 53 5.2 12.1 2.2 0.541
 AA 71 6.9 8.0 4.4   66 7.0 6.7 5.5  
 HW 233 6.4 8.8 3.5   219 6.0 8.6 3.7  
Age (years)
 < 50 94 6.2 10.7 3.1 0.797 86 5.6 10.1 2.8 0.571
 ≥ 50 268 6.5 8.8 3.7   252 6.2 8.5 3.9  
BMI (kg/m2)
 < 25 94 3.1 6.3 1.2 0.0001 87 3.1 8.4 1.4 0.0009
 25–29.99 124 7.3 11.0 3.7   117 6.5 9.5 3.8  
 ≥ 30 144 8.0 8.8 4.9   134 7.7 8.4 5.3  
Smoking history
 Never 238 5.8 8.6 3.4 0.066 225 5.4 7.8 3.4 0.046
 Ever 124 7.7 10.3 3.7   113 7.4 10.7 3.9  
Pre-RT pain score
 < 4 286 5.9 8.8 3.3 0.014 266 5.6 8.4 3.4 0.054
 ≥ 4 59 9.3 11.8 4.9   56 8.1 10.3 4.2  
Post-RT pain score
 < 4 230 5.4 8.2 3.1 0.007 226 5.3 7.8 3.2 0.014
 ≥ 4 101 8.3 9.9 4.6   99 7.9 11.0 4.8  
Tumor stage
 0 73 6.1 8.2 3.6 0.916 65 6.3 8.3 3.4 0.872
 IA-B 180 6.4 10.0 3.3   165 6.3 10.8 3.4  
 IIA-III 109 6.7 8.8 3.9   108 5.7 5.7 4.2  
Breast volume (cc)
 < 892.1 cc (median) 181 5.2 8.2 2.6 0.011 169 5.0 9.2 2.4 0.021
 ≥ 892.1 cc (median) 177 7.7 10.2 4.6   165 7.2 8.6 5.0  
Hormone therapy
 None/after RT 175 6.7 10.5 3.2 0.736 159 5.7 7.9 3.3 0.032
 AI before 97 6.7 7.7 4.8   95 7.2 10.0 4.6  
 AI during 14 4.5 4.0 3.3   14 5.1 5.3 3.8  
 Tamoxifen before 64 5.5 8.8 2.8   59 4.3 6.0 2.4  
 Tamoxifen during 12 8.2 9.3 5.1   11 12.8 21.0 5.1  
RT fractionation
 Conventional 302 6.4 9.1 3.5 0.632 289 6.2 9.2 3.5 0.575
 Hypo 60 7.0 10.2 3.5   49 5.4 7.0 3.7  
  1. 1P values from ANOVA; significant findings are in italics
  2. 2Paired t test comparing pre- and post-RT CRP
  3. Abbreviations: NHW non-Hispanic whites, AA black or African American, HW Hispanic whites, BMI body mass index, AI aromatase inhibitor, SD standard deviation, MD median
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