Table 2 Association of NNMT expression with clinicopathological characteristics in 82 breast cancer patients with a chemotherapy efficacy record
Patient characteristics | n | NNMTh (%) | Pearson’s χ2 | P |
|---|---|---|---|---|
Total | 82 | 38 (46.3) | Â | Â |
Age (years) Median = 50 | ≤ 50 (36) | 19 (52.8) | 1.069 | 0.301 |
> 50 (46) | 36 (41.3) | |||
ER | Positive (58) | 24 (41.4) | 1.962 | 0.161 |
Negative (24) | 14 (58.3) | |||
PR | Positive (53) | 23 (43.4) | 0.523 | 0.470 |
Negative (29) | 15 (51.7) | |||
HER-2 | Positive (43) | 22 (51.2) | 1.417 | 0.232 |
Negative (37) | 14 (37.8) | |||
Ki-67 | Positive (35) | 15 (42.9) | 0.081 | 0.776 |
Negative (39) | 18 (46.2) | |||
Molecular subtype | Â | Â | 3.364 | 0.339 |
 Luminal A | 20 | 6 (30.0) | ||
 Luminal B | 42 | 21 (50.0) | ||
 ERBB2 | 13 | 6 (46.2) | ||
 Basal-like | 6 | 4 (66.7) | ||
TNM | 0.115 | 0.990 | ||
 0 | 0 | 0 (0) | ||
 I | 27 | 13 (48.1) | ||
 II | 39 | 18 (46.2) | ||
 III | 14 | 6 (42.9) | ||
 IV | 2 | 1 (50.0) | ||
TNM2 | 0.393 | 0.530 | ||
 0 + I + II | 63 | 28 (44.4) | ||
 III + IV | 19 | 10 (52.6) | ||
Primary tumor size | 1.387 | 0.709 | ||
 Tis | 0 | 0 (0) | ||
 T1 | 35 | 18 (51.4) | ||
 T2 | 39 | 16 (41.0) | ||
 T3 | 5 | 3 (60.0) | ||
 T4 | 3 | 1 (33.3) | ||
Lymph node metastasis | 2.980 | 0.395 | ||
 N0 | 49 | 23 (46.9) | ||
 N1 | 19 | 9 (47.4) | ||
 N2 | 8 | 5 (62.5) | ||
 N3 | 6 | 1 (16.7) | ||
Distant metastasis | 1.770 | 0.183 | ||
 M0 | 80 | 38 (47.5) | ||
 M1 | 2 | 0 (0) | ||
Chemotherapy response | 4.807 | 0.028 | ||
 CR+PR | 32 | 10 (31.3) | ||
 SD+PD | 50 | 28 (56.0) | ||