Fig. 7

Rack1 is critical for drug-resistant breast cancer cell metastasis in vivo. a Rescued with Rack1^WT group displayed more metastatic foci on the mice lung surface than that in control and Rack1^Y246F-rescued group. b, c Hematoxylin and eosin staining showed that rescued with Rack1^WT, not Rack1^Y246F, in Rack1-silenced cells increased the number of micrometastases in the lung compared with that of the control group. Data are shown as mean ± SD; n = 8. Statistical analysis was performed by one-way ANOVA. **P < 0.01 and ^nsP > 0.05 indicate no significance