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Fig. 7 | Breast Cancer Research

Fig. 7

From: Rack1 mediates tyrosine phosphorylation of Anxa2 by Src and promotes invasion and metastasis in drug-resistant breast cancer cells

Fig. 7

Rack1 is critical for drug-resistant breast cancer cell metastasis in vivo. a Rescued with Rack1WT group displayed more metastatic foci on the mice lung surface than that in control and Rack1Y246F-rescued group. b, c Hematoxylin and eosin staining showed that rescued with Rack1WT, not Rack1Y246F, in Rack1-silenced cells increased the number of micrometastases in the lung compared with that of the control group. Data are shown as mean ± SD; n = 8. Statistical analysis was performed by one-way ANOVA. **P < 0.01 and nsP > 0.05 indicate no significance

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