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Table 1 ER status and cytonuclear grade of DCIS by age

From: Frequency of pathogenic germline variants in BRCA1, BRCA2, PALB2, CHEK2 and TP53 in ductal carcinoma in situ diagnosed in women under the age of 50 years

Age

Total

ER+

ER−

ER unknown

High grade

Int grade

Low grade

Grade unknown

40–49

555

345 (62%)

62 (11%)

148 (27%)

345 (62%)

148 (27%)

47 (8%)

15 (3%)

< 40

100

45 (45%)

26 (26%)

29 (29%)

72 (72%)

20 (20%)

7 (7%)

1 (1%)

All

655

390

88

177

417

168

54

16