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Table 5 Associations between relative telomere length and risk of breast cancer stratified by length of follow-up, Singapore Chinese Health Study

From: Association between prediagnostic leukocyte telomere length and breast cancer risk: the Singapore Chinese Health Study

Telomere length in quartile by stratification variable Cases Person-years Adjusted HR1 (95% CI)
Follow-up < 5 years
 Q1 (shortest) 29 17,272 1.00 (reference)
 Q2 42 17,329 1.42 (0.89, 2.29)
 Q3 58 17,298 1.95 (1.24, 3.06)
 Q4 (longest) 50 17,353 1.68 (1.05, 2.69)
Ptrend    0.015
Follow-up ≥ 5 years
 Q1 (shortest) 55 25,763 1.00 (reference)
 Q2 64 26,764 1.11 (0.77, 1.59)
 Q3 62 27,014 1.04 (0.72, 1.50)
 Q4 (longest) 82 27,821 1.35 (0.95, 1.92)
Ptrend    0.12
  1. CI confidence intervals, HR hazard ratio
  2. 1Hazard ratio derived from Cox proportional hazard regression model adjusted for age at sample collection, dialect group, level of education, BMI, age when period became regular, age at first live birth, number of live births, age at menopause, use of hormone therapy, use of oral contraceptives, family history of breast cancer, smoking status, alcohol consumption, weekly vigorous work or strenuous sports, and number of hours of sleep