Fig. 2

Motifs and pathways associated with super-enhancers attenuated in BRCA1^mut/+ HMECs. a List of transcription factor binding motifs enriched in super-enhancers attenuated in BRCA1^mut/+ HMECs. H3K27ac peaks within these super-enhancers were used for motif search. H3K27ac peaks within those super-enhancers shared by BRCA1^+/+ and BRCA1^mut/+ HMECs were used as background. The table is ranked by P value. b Gene Ontology (GO) analysis using genes associated with BRCA1^mut/+-lost super-enhancers. ToppGene was used for GO analysis. Pathways were ranked by FDR-adjusted P value