Table 2 Association between EmiR expression at Ext2 and clinicopathological characteristics in LBC patients
Ext2 | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
EmiR-21 | EmiR-222 | EmiR-221 | EmiR-105 | EmiR-155 | ||||||||
n | Median | p value | Median | p value | Median | p value | Median | p value | Median | p value | ||
Age (years) | < 50 | 19 | 3.975 | 0.585 | 1.851 | 0.536 | 1.705 | 0.771 | 2.534 | 0.166 | 2.173 | 0.536 |
≥ 50 | 14 | 3.033 | 2.100 | 1.718 | 11.182 | 1.401 | ||||||
Menopause | Pre | 20 | 4.159 | 0.094 | 2.250 | 0.461 | 1.890 | 0.338 | 3.916 | 0.224 | 2.177 | 0.768 |
Post | 13 | 2.192 | 1.551 | 1.422 | 10.603 | 1.507 | ||||||
T | T1–T2 | 18 | 3.668 | 0.233 | 2.382 | 0.828 | 2.238 | 0.219 | 16.929 | 0.112 | 2.601 | 0.159 |
T3–T4 | 15 | 3.246 | 1.851 | 1.286 | 3.484 | 1.819 | ||||||
N | 0 | 11 | 3.975 | 0.621 | 3.037 | 0.621 | 2.490 | 0.006* | 21.588 | 0.445 | 1.344 | 0.928 |
1–3 | 18 | 3.477 | 2.250 | 1.095 | 8.885 | 2.177 | ||||||
Estrogen receptor | Negative | 8 | 2.133 | 0.450 | 1.213 | 0.475 | 1.095 | 0.585 | 5.405 | 0.529 | 0.839 | 0.120 |
Positive | 25 | 3.933 | 2.649 | 2.000 | 11.760 | 2.173 | ||||||
Progesterone receptor | Negative | 11 | 2.192 | 0.541 | 1.338 | 0.760 | 1.787 | 0.541 | 7.327 | 0.789 | 3.224 | 0.849 |
Positive | 22 | 3.668 | 2.250 | 1.686 | 8.528 | 1.899 | ||||||
HER2 | Negative | 27 | 3.933 | 0.031* | 3.037 | 0.056 | 1.705 | 0.744 | 5.297 | 0.484 | 2.173 | 0.161 |
Positive | 6 | 0.857 | 0.536 | 41.874 | 46.810 | 0.639 | ||||||
KI67 | < 20% | 6 | 4.996 | 0.427 | 1.464 | 0.283 | 0.321 | 0.176 | 3.691 | 0.963 | 1.355 | 0.191 |
≥ 20 | 27 | 3.246 | 3.037 | 1.787 | 10.444 | 3.201 | ||||||
Perou’s classification | Basal-like | 5 | 2.192 | 0.655 | 1.338 | 0.666 | 1.286 | 0.666 | 3.484 | 0.510 | 0.983 | 0.232 |
Luminal A | 5 | 6.058 | 0.729 | 0.334 | 2.085 | 1.367 | ||||||
Luminal B | 20 | 3.324 | 3.052 | 2.038 | 16.580 | 3.459 | ||||||
HER2neu | 3 | 2.074 | 0.175 | 0.307 | 10.603 | 0.695 | ||||||