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Fig. 3 | Breast Cancer Research

Fig. 3

From: MiR-1287-5p inhibits triple negative breast cancer growth by interaction with phosphoinositide 3-kinase CB, thereby sensitizing cells for PI3Kinase inhibitors

Fig. 3

In vivo xenograft experiments of stable mature form of miR-1287-5p overexpressing SUM159 cells. MiR-1287-5p overexpressing cells were injected in the left mammary fat pad of nude mice compared to control SUM159 cells which were injected into the right site. a–c Cells with miR-1287-5p overexpression developed significantly smaller tumors compared to control cells. (d) Bar chart of histomorphometric measurements of the largest tumor area detected in HE-staining revealed significantly smaller tumor area in SUM159 miR-1287-5p overexpressing cells *p < 0.05, ***p < 0.001. (e-f) Representative histological pictures of control cells and miR-1287-5p overexpressing SUM159 (HE staining, × 4 magnification, inserts with x40 magnification)

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Breast Cancer Research

ISSN: 1465-542X

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