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Fig. 2 | Breast Cancer Research

Fig. 2

From: A subgroup of microRNAs defines PTEN-deficient, triple-negative breast cancer patients with poorest prognosis and alterations in RB1, MYC, and Wnt signaling

Fig. 2

Identification of a PTEN-low/miR-low subgroup of TNBC with exceedingly poor prognosis. Heatmaps of PTEN and five most positively correlated miRNAs in 205 TNBC (a) and in 31 PTEN-deficient (−) TNBC (b) from training cohort and top four miRNAs in 44 TNBC (c) from the validation cohort. Map colors: green, low expression; red, high expression. Kaplan-Meier survival analysis on PTEN expression in training 205 TNBC (d) and validation 44 TNBC (e). f, g Kaplan-Meier survival analysis on PTEN-low/miR-low (group “a”) in 31 PTEN(−) TNBC from training cohort or 30 PTEN(−) TNBC from validation cohort. h, i Kaplan-Meier survival analysis on 205 TNBC or 44 TNBC for group “a” versus the remaining tumors

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Breast Cancer Research

ISSN: 1465-542X

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